# Senior Scientist, Developability \[Contract\] at Bighatbiosciences

> Onsite · United States · Senior · Other · open. Source: https://alderhq.app/jobs/pinpoint%3Abighatbiosciences%3A572988 (read 2026-11-15).

## Facts (observed)

- Company: [Bighatbiosciences](https://alderhq.app/companies/bighatbiosciences)
- Location text: San Mateo, CA, CA
- Where it can be done from (inferred): Onsite · United States (evidence: "Location: San Mateo, CA, CA")
- Posted: already open when tracking began; date unknown
- First seen by alder: 2026-11-04 · last verified: 2026-11-09
- Reposted: 0 times · edited: 0 times
- Apply on the employer's site: https://bighatbiosciences.pinpointhq.com/en/postings/a785ab55-3527-4a69-a39c-1c4e7db4b8d9

## Pay and sponsorship

- Posted pay: not posted
- Market band for similar posted roles (SF Bay Area, n 672): p25 $130k, median $163k, p75 $195k

## Description (the employer's text)

The role: BigHat Biosciences is looking for a hands-on, bench-driven scientist to perform IND-enabling developability assessments on late stage drug candidates from our Milliner Platform for AI-designed therapeutics. This is a lab-based 12-month contract role, with the possibility but no guarantee of conversion to full-time position. You'll spend the majority of your time at the bench executing complex stability studies.

### Responsibilities

- Lead, design, and execute in-use dose solution studies to assess drug compatibility with administration materials.
- Develop highly sensitive protein characterization methods (qSEC, RP-HPLC, CEX, particle counting, etc) for assessing drug quality and recovery.
- Support late-stage characterization, including formulation screening, stress testing, and peptide mapping, to rank and advance lead candidates.
- Drive developability assessments (purity, stability, tolerability, biophysical properties) across programs, with strong attention to data interpretation and organization.
- Communicate with and manage external CROs for testing and analytics.
- Interpret and communicate scientific findings, propose next steps, and broadcast clearly across the organization.
- Proactively identify and scope state-of-the-art analytical tools and developability technologies.
### Skills

- PhD in Biochemistry or relevant discipline with 5+ year(s) of industry experience; exceptional non-PhD candidates with deep bench experience will be considered.
- Experience developing and optimizing sensitive analytical chromatography-based methods is a must.
- Strong background in biophysical and analytical characterization of antibodies and antibody fragments: SEC, HIC, CE-SDS, DLS, DSF, ELISA, LC-MS.
- Track record of translating complex data into clear results and recommended actions.
- Enthusiastic about learning and onboarding new technologies to expand capabilities and improve work quality, timelines, throughput or cost.

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Data: alder (https://alderhq.app). Cite https://alderhq.app/jobs/pinpoint%3Abighatbiosciences%3A572988 and the date you read it. Observed facts come from the employer's own listing; location reach, level, family and skills are inferences.