POSITION SUMMARY As a Senior Software Engineer at Natera, you will own the architecture, quality, and reliability of the systems you build. You bring deep expertise in designing scalable clinical software within a regulated healthcare environment, architecting systems with observability and testability at their core. This role is ideal for engineers with a strong automation and quality engineering foundation who are looking to expand their full-stack or backend software development scope.

Working alongside Engineering, Product Management, and Design, you will build new features and user experiences while establishing the automated quality practices that empower the team to ship rapidly and safely.

PRIMARY RESPONSIBILITIES

System Architecture & Development: Design, build, and maintain production software systems and scalable, well-tested APIs from technical specifications.
End-to-End Quality Ownership: Own the quality lifecycle of the features you develop, spanning unit, integration, and system-level validation.
Test Infrastructure & AI Tooling: Architect and maintain robust test automation frameworks, leveraging modern AI-assisted development and testing tools to accelerate engineering velocity and test coverage.
Architectural Collaboration: Partner with the architecture team on system design to ensure reliability, observability, and testability are built in from the ground up.
CI/CD Integration: Embed automated test suites directly into CI/CD pipelines to support continuous build, test, and deployment cycles.
Technical Leadership: Conduct thorough code reviews focused on functionality, maintainability, and test coverage while mentoring peers on software design and quality best practices.
Cross-Functional Alignment: Collaborate with Product Managers to translate product designs into comprehensive verification and validation strategies, and clearly document and triage discovered issues with affected teams.
Compliance: Maintain current status on all required Natera compliance and regulatory training.

QUALIFICATIONS

Bachelor’s degree in Computer Science, a related technical field, or equivalent practical experience.
7+ years of experience across software development, test automation, and quality engineering.
Proven track record building and maintaining production applications and automation frameworks in Java and Python.
Hands-on experience designing microservices and scalable cloud-native applications, preferably on AWS.
Deep familiarity with the full software development lifecycle (SDLC), with an emphasis on shifting quality left into every phase.

KNOWLEDGE, SKILLS, AND ABILITIES

Languages & Paradigms: Strong Object-Oriented Programming (OOP) fundamentals in Java and Python.
Testing & Automation: Proficiency with modern testing frameworks and libraries such as Playwright, Selenium, JUnit, and TestNG.
Backend & Data: Experience with REST API design and testing, relational databases, and SQL (PostgreSQL preferred).
Cloud & Infrastructure: Familiarity with Docker/containerization, CI/CD pipeline configuration, and core AWS services (e.g., SQS, S3, SNS, MSK).
Core Competencies: Strong analytical and debugging skills with a keen eye for system dependencies and integration points, paired with clear cross-team communication.

#LI-DNI

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$125,600—$157,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.