MyOme is a clinical whole genome analysis company helping individuals and families understand their risk for disease. As a leader in polygenic and AI-based integrative risk modeling, we combine genome sequencing with AI-driven analytics and clinical data to deliver a lifetime of clinically meaningful, actionable insights, from proactive risk assessment to rare disease diagnosis. Our laboratory is CLIA-certified and CAP-accredited, and we’re based in Menlo Park, California.

Our team brings together scientists, engineers, clinicians, and professionals across disciplines, united by a shared purpose: making genomic insight a routine part of everyday healthcare. We put patients first and hold ourselves to the scientific and clinical rigor that families and their clinicians depend on.

Joining MyOme means contributing your expertise to work that matters for patients and families. Whether you’re advancing our science and technology, supporting the clinicians and patients we serve, or strengthening our operations, you’ll help turn genomic discoveries into better care.

Position Overview

We’re seeking a hands-on Laboratory Director to lead clinical testing, strengthen laboratory operations, and bring new genomic assays into practice. You’ll own testing quality, guide interpretation and reporting, and build a team that delivers accurate results reliably.

You know how to turn scientific ambition into validated tests, clear workflows, and completed projects. You bring sound clinical judgment, strong diagnostic experience, and the ability to move work forward across teams.

What You'll Do

Lead clinical testing: Oversee test performance, variant interpretation, and report sign-out within your authorized scope.
Bring assays to launch: Drive validation and clinical implementation with R&D and Bioinformatics, defining controls, acceptance criteria, and test limitations.
Build the team: Hire, mentor, and develop laboratory staff with clear expectations and accountability.
Advance technology: Help implement whole genome sequencing, long-read platforms, automation, and better LIMS workflows.
Scale operations: Improve turnaround time, capacity, and cost while maintaining testing quality.

What You'll Need

MD, DO, or PhD with relevant board certification and qualifications to direct the laboratory’s high-complexity testing.
CA license, NY preferred
5 or more years in clinical molecular diagnostics, including leadership and genomic interpretation and reporting.
A track record of taking assays from development through validation into routine clinical use.
Deep knowledge of NGS, human genetics, variant interpretation, and laboratory quality systems.
Strong judgment, concise communication, and the ability to lead across scientific, clinical, and operational teams.
Commitment to consistent onsite leadership.
Experience with long-read sequencing, laboratory scaling, automation, and New York State submissions is a plus.

Location, Compensation, and Benefits

Location: Hybrid, 2–3 days onsite at our Menlo Park, CA laboratory campus; Bay Area candidates preferred. Remote in the US considered for the right candidate.
Compensation: Annual salary range of $200,000 - $240,000, commensurate with experience. This role is eligible for equity.

San Francisco Bay Area pay range

$200,000—$240,000 USD

Benefits

Comprehensive healthcare coverage (Health, Dental, and Vision)
401K
Professional development opportunities
Company-sponsored off-sites and team meals during in-person meetings
Direct access to company leadership and the opportunity for career growth

Equal Employment Opportunity and Reasonable Accommodations

MyOme is an equal opportunity employer. We make employment decisions without regard to race, color, ancestry, national origin, religion, age, sex (including pregnancy, childbirth, breastfeeding, and related medical conditions), gender, gender identity or expression, sexual orientation, marital status, physical or mental disability, medical condition, genetic information, military or veteran status, reproductive health decision-making, or any other characteristic protected by applicable law. MyOme provides reasonable accommodations to qualified applicants with disabilities and as otherwise required by law. To request an accommodation during the application or interview process, please contact hr@myome.com.