# Medical Director, Medical Affairs at Compass Pathways

> Remote · United States · Director+ · Other · open. Source: https://alderhq.app/jobs/greenhouse%3Acompasspathways%3A5014052101 (read 2026-11-08).

## Facts (observed)

- Company: [Compass Pathways](https://alderhq.app/companies/compass-pathways)
- Location text: United States; Remote - US
- Where it can be done from (inferred): Remote · United States (evidence: "Location: United States; Remote - US")
- Posted: 2026-10-22 (17 days ago)
- First seen by alder: 2026-11-04 · last verified: 2026-11-07
- Reposted: 0 times · edited: 0 times
- Apply on the employer's site: https://job-boards.eu.greenhouse.io/compasspathways/jobs/5014052101

## Pay and sponsorship

- Posted pay: $270k–$320k per year (from the listing's pay field)
- Market band for similar posted roles (United States, n 3921): p25 $171k, median $215k, p75 $260k

## Description (the employer's text)

Company introduction:

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to unlocking urgently needed new treatment options in mental health care.

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD.

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing. - Compass Pathways

Job overview:

The Medical Director, Medical Affairs will serve as a subject matter expert representing professional medical expertise within the Medical Affairs function, with an initial focus on treatment-resistant depression (TRD) and investigational psychedelic therapeutics. This individual will provide clinical perspective, medical judgment, and thought partnership to Medical Affairs leadership and functional teams.

The Medical Director will contribute to the execution of Medical Affairs strategy through critical evaluation of clinical evidence, development of evidence-generation initiatives, and engagement with external medical experts. Working collaboratively with Medical Affairs and cross-functional partners, the Medical Director will help ensure that scientific initiatives are clinically relevant, evidence-based, and responsive to evolving needs in psychiatric care.

The successful candidate will bring deep expertise in psychiatry, the ability to critically analyze emerging evidence, and established relationships within the medical and scientific community. This individual will be expected to proactively identify important clinical knowledge gaps, recommend approaches to addressing them, and take an active role in developing and advancing research initiatives that inform clinical practice.

Location: Remote in the United States.

Reports to: Executive Director, Medical Affairs.

Roles and Responsibilities

(include but are not limited to):

### Therapeutic Area Expertise and Medical Guidance

- Serve as a medical subject matter expert in TRD, interventional psychiatry, and emerging psychiatric treatments
- Provide clinical insights and recommendations to inform Medical Affairs priorities and initiatives
- Critically evaluate clinical trial results, scientific literature, and evolving treatment guidelines to inform medical strategy and decision-making
- Partner with Scientific Communications, Medical Information, Medical Education, and Field Medical leadership to ensure clinical relevance and consistency across Medical Affairs activities
- Identify emerging developments and clinical practice considerations that may inform future Medical Affairs priorities
- Provide medical expertise to support future therapeutic indications and pipeline opportunities, as appropriate
### Evidence Generation and Research

- Lead the development of Medical Affairs research proposals and evidence-generation initiatives aligned with organizational scientific priorities
- Collaborate with Clinical Development, Clinical Sciences, Biostatistics, HEOR, and other stakeholders to develop rigorous research concepts, protocols, and analysis plans
- Provide medical oversight and direction for Medical Affairs-sponsored research, including real-world evidence studies, observational research, and other post-approval evidence-generation activities, as appropriate

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Data: alder (https://alderhq.app). Cite https://alderhq.app/jobs/greenhouse%3Acompasspathways%3A5014052101 and the date you read it. Observed facts come from the employer's own listing; location reach, level, family and skills are inferences.
