# Executive Director, Commercial Counsel at Xenon

> Hybrid · United States · Director+ · Other · open. Source: https://alderhq.app/jobs/ashby%3Axenon%3A55ab8a5d-0642-4d0e-afa3-bd067da0290f (read 2026-11-10).

## Facts (observed)

- Company: [Xenon](https://alderhq.app/companies/xenon)
- Location text: Boston
- Where it can be done from (inferred): Hybrid · United States (evidence: "Location: Boston")
- Posted: 2026-11-04 (6 days ago)
- First seen by alder: 2026-11-07 · last verified: 2026-11-08
- Reposted: 0 times · edited: 0 times
- Apply on the employer's site: https://jobs.ashbyhq.com/xenon/55ab8a5d-0642-4d0e-afa3-bd067da0290f

## Pay and sponsorship

- Posted pay: $289k–$365k per year (from the listing's pay field)
- Market band for similar posted roles (Boston, n 242): p25 $197k, median $222k, p75 $260k

## Description (the employer's text)

Who We Are:

Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.

What We Do:

We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we submitted a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 and XEN1720 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are being developed for pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

About the Role:

We are seeking an Executive Director, Commercial Counsel to serve as a senior legal leader and strategic partner to Xenon's rapidly evolving commercial organization. As Xenon advances toward commercialization, this individual will provide strategic legal leadership across brand strategy, commercialization and launch readiness, partnering closely with senior leaders across Commercial, Medical Affairs, Market Access, Corporate Affairs, Regulatory, Compliance and other functions.

The Executive Director will anticipate and address complex legal and regulatory issues associated with building and operating a commercial-stage organization, translate evolving legal requirements into pragmatic business solutions, and help establish scalable approaches, governance and legal capabilities that enable Xenon's long-term commercial strategy while appropriately managing enterprise risk. This position reports to the Vice President, Legal & Compliance and will be based out of Boston, MA, USA in our Needham office. This is a hybrid position requiring 2-3 days in the office per week. We will consider remote locations for exceptional candidates. The level of the position will be commensurate with the candidate’s education and industry experience.

### RESPONSIBILITIES

Serve as senior legal counsel to cross-functional brand leadership, participating in early strategic planning and advising on the legal and regulatory implications of brand strategy, disease awareness, promotional strategy, scientific exchange, and external engagement.

Provide strategic legal leadership supporting Xenon's transition from a clinical-stage to commercial-stage organization, proactively identifying legal, regulatory and operational considerations associated with launch readiness and building scalable approaches to support the evolving commercial model.

Serve as strategic legal business partner to all customer-facing functions, including Commercial, Market Access, Medical Affairs, and Corporate Affairs.

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Data: alder (https://alderhq.app). Cite https://alderhq.app/jobs/ashby%3Axenon%3A55ab8a5d-0642-4d0e-afa3-bd067da0290f and the date you read it. Observed facts come from the employer's own listing; location reach, level, family and skills are inferences.
