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Parallel Bio

Scientist (Cell & Tissue Operations)

San Francisco, CAOnsite · United States
FullTime · Platform
POSTED 6 OCTVERIFIED 1D AGO
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Pay · posted
$125k–140k
mkt median $155k
Open for
30d
since 6 Oct
Hiring · 30d
1
0 net · open roles
CSS

The Mission

Drug discovery has a translation problem: more than 95% of drugs that succeed in animal models fail in humans. We're building the alternative: human-first drug discovery, powered by organoids and AI, running on real human biology from the very first experiment.

Our platform is 87% concordant with clinical patient data - a vast improvement over the 3% translational success rate of animals. We’ve demonstrated the ability to model immunotoxicology, immunogen stimulation, and two autoimmune diseases with more on the way. Numerous pharma partners including 3 Fortune 500 companies are already using the platform. We've raised ~$30M from AIX Ventures, Marc Benioff, Jeff Dean, and Y Combinator. With the FDA Modernization Act 3.0 and the FDA's March 2026 validation framework, the regulatory tailwinds only continue to get stronger.

The opportunity ahead of the company is generational: build the first scaled engine for generating real human biological data, and use it to fundamentally change how medicines are discovered.

The role

Note to candidates: this describes a strong profile, not a checklist. If you don't match every point but believe you'd do this job well, please apply.

We are hiring a Scientist I to run the hands-on cell and tissue culture work that every Parallel Bio program depends on. You will process human tissue, build and maintain cell banks, run immunological assays, and turn what works at the bench into robust, documented processes.

This role is shared between Technical Operations and Science. You will split time between executing partner studies and strengthening the systems behind them: SOPs, cell inventory, and process consistency. It suits a scientist who likes the bench and has a high standard for technical accuracy, precision, and data quality.

Why join Parallel Bio

Human-relevant immunology: your work generates human immune data that shapes real drug development decisions

Early-team impact: the processes you build become how the company runs as it scales

Partner-facing science: work directly on studies for biopharma partners

Room to grow: scope expands as you take on ownership, toward Scientist II and process leadership

What you'll do

Tissue processing and cell culture

Process human lymphoid tissue and primary cells into single-cell suspensions and organoid cultures

Apply donor acceptance criteria and track donor metadata to manage donor-to-donor variability

Optimize and troubleshoot scientific protocols as needed in a data-driven manner

Execute partner study protocols on schedule under aseptic technique

Cell banking and cryopreservation

Cryopreserve, thaw, and recover primary human cells with consistent viability and yield

Execute cell banking runs with full chain of custody from donor to vial

Maintain the LN2 inventory: storage, sample tracking, and reconciliation

Assays and immune readouts

Independently execute flow cytometry for immunophenotyping and study endpoint measurements

Independently execute un functional assays (e.g., ELISA, MSD, ELISpot, cytotoxicity), plus imaging or qPCR as programs require

Analyze data (FlowJo, Prism, or equivalent) and contribute to study summaries for partners. Clearly communicate data and findings to stakeholders.

Process, documentation, and lab operations

Draft and revise SOPs, and help train new team members on them

Support the move from research-grade documentation toward GLP-like rigor

Maintain core equipment and reagent inventory, and support EH&S programs

What you'll bring

PhD in immunology, cell biology, bioengineering, or a related field with 0–2 years of postdoctoral or industry experience; an MS with 5+ years of relevant industry experience; or a BS with 8+ years of relevant industry experience

Hands-on proficiency in primary human cell or tissue culture under strict aseptic technique

Hands-on proficiency in cryopreservation: freezing, thawing, and tracking cell stocks

Hands-on proficiency in flow cytometry, plus at least one other immune assay method (e.g., ELISA, MSD, ELISpot, Luminex)

Strong documentation habits grounded in data integrity (ALCOA+) principles: detailed electronic notebook entries, clear protocols, and records someone else can follow

Source · Parallel BioFirst seen 3 NovOriginal ↗