# Automation Engineer Associate II at BillionToOne

> Location unclear · Junior · Software engineering · open. Source: https://alderhq.app/jobs/ashby%3Abilliontoone%3A5a6e9518-e83f-4f0e-a771-c2cd4f70a4ec (read 2026-11-06).

## Facts (observed)

- Company: [BillionToOne](https://alderhq.app/companies/billiontoone)
- Location text: Union City
- Where it can be done from (inferred): Location unclear (evidence: "Location: Union City")
- Posted: 2026-10-19 (18 days ago)
- First seen by alder: 2026-11-03 · last verified: 2026-11-04
- Reposted: 0 times · edited: 0 times
- Apply on the employer's site: https://jobs.ashbyhq.com/billiontoone/5a6e9518-e83f-4f0e-a771-c2cd4f70a4ec
- Skills listed (inferred): Python

## Pay and sponsorship

- Posted pay: not posted
- H-1B filings at this company for similar roles, FY26: 5, median offered wage $111k ([US DOL OFLC LCA disclosure data](https://www.dol.gov/agencies/eta/foreign-labor/performance))

## Description (the employer's text)

### A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for an Automation Engineer Associate II (level commensurate with experience and interview scores) to join our growing Process Engineering team responsible for innovative solutions to support the high-complexity and high-growth clinical laboratory. This is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. The Automation Engineer reports to the Automation Engineering Manager and is an onsite position. This role will help to build upon the strong technology and execution found within BTO’s walls, and will help us pave the way for replicating our prenatal success in the oncology space. This is considered an onsite role and will require the majority of days to be spent in the office at either the Menlo Park or Union City sites.

### Responsibilities

End-to-end development, design, integration, and validation of automation systems and protocols on liquid handling platforms (Hamilton, Lynx, Agilent Bravo etc.) in the clinical laboratory

Contribute to integration efforts between liquid handlers and LIMS, utilizing APIs/drivers to support bi-directional data transfer and sample tracking

Identify, develop, and implement process improvements to design and improve robust laboratory procedures

Collaborate with the clinical and R&D teams to transfer new products and procedures onto the automated platforms

Provide training and guidance to employees in the operation, maintenance, and troubleshooting of new equipment

Develop and prepare documentation for procedure changes, instrument validations, IQ/OQ/PQ, standard operating procedures, and related documents

### Qualifications

BS or higher in Engineering, Biology, Microbiology, Biophysics, Biochemistry, or related field

1 to 3 years of experience in assay automation on liquid handlers (i.e. Hamilton, Beckman, Agilent, Tecan, Dynamic Devices)

Experience in a semi-automated laboratory environment

Technical proficiency in laboratory automation and systems development

Strong multi-tasking, project management, organizational, communication, and documentation skills

Software development experience in one or more languages (Python preferred)

Strong laboratory understanding with experience in next-generation sequencing library preparation

### Nice-to-Haves

Certification in one of the major liquid handling systems (Hamilton, Beckman, Agilent, Tecan)

Experience working under regulatory environments such as CLIA, CAP, or FDA

Experience with Clarity LIMS or other LIMS systems

Experience with integrated systems

### Benefits And Perks

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients

Open, transparent culture that includes weekly Town Hall meetings

The ability to indirectly or directly change the lives of hundreds of thousands patients

Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%

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Data: alder (https://alderhq.app). Cite https://alderhq.app/jobs/ashby%3Abilliontoone%3A5a6e9518-e83f-4f0e-a771-c2cd4f70a4ec and the date you read it. Observed facts come from the employer's own listing; location reach, level, family and skills are inferences.
